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Allergy Clinical Papers

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Download a range of clinical paper summaries detailing research in the treatment of CMPA. 

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Inside the tin: A guide to Infant Formula for the management of CMPA (Part 1)

Nutritional support in early life is an essential part of the clinical management of infants with food allergies, such as cows’ milk protein allergy (CMPA). When breastfeeding is not possible or for mixed feeding, there are several different types of infant formulas available to manage CMPA. How do you select the most appropriate one?

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Inside the tin: Advancing the management of CMPA (Part 2)

In recent years, there has been a paradigm shift in how cow’s milk protein allergy (CMPA) is managed. Previously, the goal was to achieve symptom relief with a focus on allergen avoidance. More recently research has focused on additional nutritional factors that support the gut microbiota and immune system, such as prebiotic oligosaccharides, synbiotics and lactose.

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Boosting Immunity of Cow’s Milk Protein Allergy Infants with Synbiotics

This double-blind randomized controlled trial, demonstrates how Syneo helps transform the dietary management of Cow’s Milk Protein Allergy, strengthening the immune system via modulation of the gut microbiota.

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Multi-centre trial shows beneficial effect of synbiotics on atopic dermatitis in infants.

Learn about how this double blind, placebo-controlled multi-centre trial showed positive modulation of the intestinal microbiota in infants with atopic dermatitis managed with an extensively hydrolysed formula containing synbiotics.

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Effects on growth, tolerance and hypoallergencity of amino acid-based formula with synbiotics

This randomised controlled trial demonstrated that an amino acid formula with synbiotics is safe, well-tolerated and promotes normal growth. The formula was also shown to be hypoallergenic in infants with CMPA.

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Synbiotics support adequate growth and tolerance in healthy infants

This randomised, controlled, double blind, prospective.multi-centre study evaluated the impact on growth and tolerance of an extensively hydrolysed formula containing synbiotics in healthy infants.

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Synbiotics to supplement proper nutrition for CMA

This was the first study done to demonstrate that amino-acid formula with synbiotic supplements supported a growth rate amongst infants with CMA similar to AAF without synbiotics

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AAF containing synbiotics improves gut microbiota in infants with CMA

This randomised controlled trial shows that the use of synbiotics supplemented amino-acid formula for infants with a suspected CMA improved the growth of healthy gut microbiota to nearly the same level as healthy breastfed infants.

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Randomised controlled trial shows benefits of using AAF containing synbiotics in relation to infection and medication usage rates

Further support for the use of synbiotics in amino-acid formula to improve healthy gut microbiota in infants with CMPA.

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